25D-NB3OMe

A synthetic psychedelic compound

25D-NB3OMe is a synthetic psychedelic compound that belongs to the NBOMe class of phenethylamines. It is a derivative of the 2C family of psychedelics, specifically related to 2C-D, and is known for its potent agonistic activity at the 5-HT2A receptor.

Chemical Structure and Properties

25D-NB3OMe is chemically classified as a phenethylamine, with a methoxybenzyl group attached to the nitrogen atom. The presence of the 2,5-dimethoxy-4-bromo substitution pattern on the phenyl ring is characteristic of the NBOMe series, which are known for their high potency and affinity for the 5-HT2A receptor.

The compound's IUPAC name is 2-(2,5-Dimethoxy-4-bromo-3-methoxyphenyl)-N-(2-methoxybenzyl)ethanamine, and it has a molecular formula of C18H22BrNO4. The molecular weight is approximately 396.28 g/mol.

Pharmacology

25D-NB3OMe acts primarily as a potent agonist at the 5-HT2A receptor, which is the primary target for classical psychedelics such as LSD and psilocybin. This receptor is part of the serotonin receptor family and is involved in the modulation of mood, perception, and cognition.

The compound's high affinity for the 5-HT2A receptor is responsible for its psychedelic effects, which can include altered sensory perception, changes in mood, and visual hallucinations. The potency of 25D-NB3OMe is significantly higher than that of its parent compound, 2C-D, due to the presence of the NBOMe group.

Effects and Risks

The effects of 25D-NB3OMe are similar to those of other psychedelics, with users reporting intense visual and auditory hallucinations, altered perception of time, and profound changes in thought processes. However, due to its high potency, the risk of overdose and adverse effects is also increased.

Adverse effects can include vasoconstriction, tachycardia, hypertension, and in severe cases, seizures or serotonin syndrome. The safety profile of 25D-NB3OMe is not well-established, and its use is associated with significant risks, particularly when used in uncontrolled settings.

Legal Status

As of the current date, 25D-NB3OMe is not specifically controlled under international drug treaties. However, its legal status may vary by country, and it may be subject to analogue laws that control substances with similar chemical structures and effects.

Research and Applications

Research on 25D-NB3OMe is limited, and it is primarily used in scientific studies to understand the structure-activity relationships of psychedelic compounds. Its high potency makes it a useful tool for studying the 5-HT2A receptor and its role in psychedelic experiences.

Also see

• NBOMe series
• 2C family
• Psychedelic drug
• Serotonin receptor
• 5-HT2A receptor