25F-NBOH

A synthetic psychedelic compound

25F-NBOH is a synthetic psychedelic compound that belongs to the N-benzylphenethylamine class. It is a derivative of the phenethylamine 2C family, specifically related to 2C-I, and is known for its potent agonistic activity at the 5-HT_2A receptor. This compound is part of a series of N-benzyl derivatives of the 2C family, which also includes compounds like 25I-NBOMe and 25C-NBOMe.

Chemical Structure and Properties

25F-NBOH is chemically known as 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine. It features a bromine atom at the 4-position of the phenyl ring, which is a common modification in this class of compounds to enhance receptor binding affinity. The presence of methoxy groups at the 2 and 5 positions of the phenyl ring is characteristic of the 2C family of psychedelics.

Pharmacology

25F-NBOH acts primarily as a potent agonist at the 5-HT_2A receptor, which is the primary target for classical psychedelics such as LSD and psilocybin. The activation of this receptor is responsible for the psychedelic effects experienced by users. The compound also shows affinity for other serotonin receptors, but its effects are predominantly mediated through 5-HT_2A.

Effects

The effects of 25F-NBOH are similar to those of other psychedelics, including altered perception of time and space, visual hallucinations, and changes in mood and thought patterns. The onset of effects typically occurs within 30 to 90 minutes after administration, with the duration lasting 6 to 10 hours. Users have reported both positive experiences, such as enhanced creativity and introspection, and negative experiences, such as anxiety and paranoia.

Safety and Toxicity

The safety profile of 25F-NBOH is not well-established, as it is a relatively new compound with limited research. However, due to its high potency, there is a risk of overdose and adverse effects, particularly when used in combination with other substances. As with other NBOMe compounds, there have been reports of severe adverse reactions, including seizures and cardiovascular complications.

Legal Status

The legal status of 25F-NBOH varies by country. In some jurisdictions, it may be classified as a controlled substance, while in others it remains unscheduled. Users should be aware of the legal implications of possessing or distributing this compound in their region.

Also see

• Psychedelic drug
• Serotonin receptor
• 2C family
• 25I-NBOMe
• 25C-NBOMe

Receptor Ligands
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Class	Not specified
Function	Not specified
Endogenous Ligands	None listed
Agonists	None listed
Antagonists	None listed
Partial Agonists	None listed
Inverse Agonists	None listed
Allosteric Modulators	None listed
Related Receptors	None listed