25P-NBMD

25P-NBMD is a synthetic compound that belongs to the family of phenethylamines, specifically a derivative of the 2C family of psychedelic phenethylamines. It is structurally related to 25I-NBOMe and 25C-NBOMe, which are known for their potent hallucinogenic effects. 25P-NBMD is a lesser-known analog that has been studied for its pharmacological properties and potential effects on the human body.

Chemical Structure and Properties

25P-NBMD is chemically known as 2-(4-propoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine. It is a derivative of the 2C-P compound, with the addition of a methoxybenzyl group, which is characteristic of the NBOMe series. This modification is known to significantly increase the potency of the compound compared to its parent phenethylamine.

The chemical structure of 25P-NBMD can be represented as follows:

• Molecular Formula: C20H27NO3
• Molecular Weight: 329.44 g/mol

Pharmacology

25P-NBMD acts primarily as a potent agonist at the 5-HT2A receptor, which is a subtype of the serotonin receptor. This receptor is known to play a crucial role in the modulation of mood, perception, and cognition, and is the primary target for many psychedelic substances.

The binding affinity of 25P-NBMD to the 5-HT2A receptor is believed to be high, similar to other compounds in the NBOMe series, which contributes to its potent psychoactive effects. However, detailed studies on its pharmacokinetics and metabolism are limited.

Effects

The effects of 25P-NBMD are not well-documented in scientific literature, but it is presumed to produce effects similar to other NBOMe compounds, which may include:

• Visual and auditory hallucinations
• Altered perception of time and space
• Euphoria
• Increased sensory perception

Due to its potency, there is a significant risk of overdose, which can lead to severe adverse effects such as agitation, confusion, hypertension, and in extreme cases, seizures or death.

Legal Status

The legal status of 25P-NBMD varies by country. In many jurisdictions, it is classified as a controlled substance due to its structural similarity to other banned NBOMe compounds. It is important for researchers and users to be aware of the legal implications of possessing or distributing this compound.

Research and Applications

Research on 25P-NBMD is limited, and it is primarily of interest in the field of psychopharmacology for its potential to provide insights into the functioning of the serotonin system and the effects of psychedelic compounds. However, due to its potent effects and potential for harm, it is not widely used in clinical or therapeutic settings.

Safety and Toxicity

The safety profile of 25P-NBMD is not well-established. As with other NBOMe compounds, there is a risk of toxicity, particularly at high doses. Users should exercise caution and be aware of the potential for serious adverse effects.

Also see

• 25I-NBOMe
• 25C-NBOMe
• 2C-P
• Psychedelic phenethylamines
• 5-HT2A receptor