25TFM-NBF

From WikiMD's Wellness Encyclopedia


25TFM-NBF is a synthetic compound that belongs to the class of phenethylamines. It is a derivative of the 2C family of psychedelic phenethylamines, which are known for their psychoactive properties. The compound is characterized by the presence of a trifluoromethyl group and a nitrobenzofuran moiety, which contribute to its unique pharmacological profile.

Chemical Structure[edit | edit source]

The chemical structure of 25TFM-NBF is based on the phenethylamine backbone, which is a common structure in many psychoactive compounds. The trifluoromethyl group is attached to the benzene ring, enhancing the compound's lipophilicity and potentially affecting its interaction with biological targets. The nitrobenzofuran moiety is another distinctive feature, which may influence the compound's binding affinity and selectivity for certain receptors.

Pharmacology[edit | edit source]

25TFM-NBF is believed to act primarily as a serotonin receptor agonist, similar to other compounds in the 2C family. It is thought to have a high affinity for the 5-HT2A receptor, which is associated with the psychedelic effects of these compounds. The trifluoromethyl group may enhance the compound's potency and duration of action by increasing its metabolic stability.

Synthesis[edit | edit source]

The synthesis of 25TFM-NBF involves several steps, starting from commercially available precursors. The introduction of the trifluoromethyl group is typically achieved through a Friedel-Crafts acylation reaction, followed by nitration to introduce the nitro group. The final step involves the formation of the benzofuran ring, which can be accomplished through a cyclization reaction.

Legal Status[edit | edit source]

The legal status of 25TFM-NBF varies by country. In some jurisdictions, it may be classified as a controlled substance due to its structural similarity to other known psychoactive compounds. Researchers and chemists should be aware of the legal implications of working with this compound.

Potential Applications[edit | edit source]

While 25TFM-NBF is primarily studied for its psychoactive properties, it may also have potential applications in neuroscience research. Its ability to selectively target serotonin receptors could make it a useful tool for studying the role of these receptors in various neurological processes.

Safety and Toxicology[edit | edit source]

As with many research chemicals, the safety and toxicology profile of 25TFM-NBF is not well-established. Researchers should exercise caution and adhere to appropriate safety protocols when handling this compound. Potential risks include neurotoxicity, cardiovascular effects, and psychological disturbances.

Also see[edit | edit source]



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Contributors: Prab R. Tumpati, MD