25P-NB4OMe

25P-NB4OMe is a synthetic psychedelic compound that belongs to the NBOMe class of drugs. It is a derivative of the phenethylamine 2C-P and is known for its potent hallucinogenic effects. This compound is primarily used in scientific research and has been studied for its interactions with the 5-HT2A receptor.

Chemical Structure and Properties

25P-NB4OMe is chemically known as 2-(4-propyl-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine. It is a member of the NBOMe series, which are N-benzyl derivatives of the 2C family of phenethylamines. The addition of the 2-methoxybenzyl group to the nitrogen atom significantly increases the compound's affinity for the 5-HT2A receptor, making it a potent agonist.

The molecular formula of 25P-NB4OMe is C21H29NO3, and it has a molar mass of 343.46 g/mol. The compound is typically synthesized in a laboratory setting and is not found naturally.

Pharmacology

25P-NB4OMe acts primarily as a potent agonist at the 5-HT2A receptor, which is the primary target for most psychedelic compounds. Activation of this receptor is responsible for the hallucinogenic effects experienced by users. The compound may also interact with other serotonin receptors, but its primary action is at the 5-HT2A site.

The effects of 25P-NB4OMe are similar to those of other NBOMe compounds, including visual and auditory hallucinations, altered perception of time, and changes in mood and thought processes. The onset of effects typically occurs within 30 to 90 minutes after administration, with the peak effects lasting several hours.

Safety and Toxicity

The safety profile of 25P-NB4OMe is not well-established, as it is a relatively new compound with limited research. However, like other NBOMe compounds, it is known to be highly potent, and there have been reports of severe adverse effects, including vasoconstriction, seizures, and cardiac arrest. Due to its potency, there is a significant risk of overdose, especially when used recreationally.

Legal Status

The legal status of 25P-NB4OMe varies by country. In many jurisdictions, it is classified as a controlled substance due to its structural similarity to other banned NBOMe compounds. Researchers interested in studying 25P-NB4OMe must typically obtain special licenses and adhere to strict regulations.

Research and Applications

Research on 25P-NB4OMe is limited, but it is of interest to scientists studying the structure-activity relationships of psychedelic compounds. Understanding how modifications to the phenethylamine structure affect receptor binding and activity can provide insights into the development of new therapeutic agents for psychiatric disorders.

Also see

• NBOMe
• 2C-P
• 5-HT2A receptor
• Psychedelic research