5-MeO-4,N,N-TMT

5-MeO-4,N,N-TMT (5-Methoxy-4,N,N-trimethyltryptamine) is a synthetic compound belonging to the tryptamine class. Tryptamines are a group of monoamine alkaloids that can be found in nature or synthesized in laboratories. They are structurally similar to the neurotransmitter serotonin and are known for their psychoactive properties.

Chemical Structure and Properties

5-MeO-4,N,N-TMT is a derivative of tryptamine, characterized by the presence of a methoxy group at the 5-position and two methyl groups attached to the nitrogen atom of the ethylamine side chain. The chemical formula for 5-MeO-4,N,N-TMT is C14H20N2O, and its molecular weight is 232.32 g/mol.

The compound is a white to off-white crystalline powder that is typically synthesized in a laboratory setting. It is soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO) but has limited solubility in water.

Pharmacology

5-MeO-4,N,N-TMT is believed to act as a partial agonist at the 5-HT2A receptor, similar to other psychedelic tryptamines. The 5-HT2A receptor is a subtype of the serotonin receptor that is implicated in the modulation of mood, cognition, and perception. Activation of this receptor is thought to be responsible for the psychedelic effects of compounds like LSD, psilocybin, and DMT.

The pharmacokinetics of 5-MeO-4,N,N-TMT, including its absorption, distribution, metabolism, and excretion, have not been extensively studied. However, it is likely that the compound is metabolized in the liver by the cytochrome P450 enzyme system, similar to other tryptamines.

Effects

The psychoactive effects of 5-MeO-4,N,N-TMT have not been well-documented in scientific literature. Anecdotal reports suggest that it may produce effects similar to other 5-methoxytryptamines, such as altered perception, changes in mood, and visual hallucinations. The onset, duration, and intensity of these effects can vary depending on the dose and route of administration.

Safety and Toxicity

There is limited information available on the safety and toxicity of 5-MeO-4,N,N-TMT. As with other research chemicals, the potential risks associated with its use are not well understood. It is important for researchers to exercise caution and adhere to appropriate safety protocols when handling this compound.

Legal Status

The legal status of 5-MeO-4,N,N-TMT varies by country. In some jurisdictions, it may be classified as a controlled substance, while in others it may be legal to possess and use for research purposes. Researchers should consult local regulations to ensure compliance with applicable laws.

Also see

• Tryptamine
• 5-MeO-DMT
• Psychedelic drug
• Serotonin receptor