Dimenhydrinate
(Redirected from Hydrinate)
What is Dimenhydrinate?[edit | edit source]
- Dimenhydrinate (Dramamine; Dramamine Chewable) is a first generation antihistamine that is used for treatment or prevention of motion sickness or symptoms of nausea and dizziness.
What are the uses of this medicine?[edit | edit source]
Dimenhydrinate (Dramamine; Dramamine Chewable) is used for prevention and treatment of these symptoms associated with motion sickness:
How does this medicine work?[edit | edit source]
- Dimenhydrinate (dye" men hye' dri nate) is the 8-chlorotheophylline salt of diphenhydramine and, thus, combines a first generation antihistamine with a xanthine that is added to counteract the drowsiness caused by diphenhydramine.
Who Should Not Use this medicine ?[edit | edit source]
This medicine cannot be used in patients who:
- in children under 2 years of age unless directed by a doctor.
What drug interactions can this medicine cause?[edit | edit source]
- Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Be sure to mention any of the following:
- aminoglycoside antibiotics such as such as amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), neomycin (Neo-Rx, Neo-Fradin), netilmicin (Netromycin), paromomycin (Humatin), streptomycin, and tobramycin (Tobi, Nebcin)
- antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil)
- antihistamines, such as diphenhydramine
- cough and cold medications
- ipratropium (Atrovent)
- medications for anxiety, irritable bowel disease, mental illness, Parkinson's disease, seizures, ulcers, or urinary problems
- narcotic or strong pain relievers or muscle relaxants
- sedatives
- sleeping pills
- tranquilizers
Is this medicine FDA approved?[edit | edit source]
- It was approved as an over-the-counter agent in 2004 and is used largely for prevention of motion sickness and nausea.
How should this medicine be used?[edit | edit source]
Recommended dosage:
- To prevent motion sickness, the first dose should be taken 1/2 to 1 hour before starting activity.
To prevent or treat motion sickness, use the following dosing:
Adults and children 12 years and over:
- 1-2 tablets every 4-6 hours; not more than 8 tablets in 24 hours, or as directed by a doctor
Children 6 years to under 12 years:
- 1/2-1 tablet every 6-8 hours; not more than 3 tablets in 24 hours, or as directed by a doctor
Children 2 years to under 6 years:
- 1/4-1/2 tablet every 6-8 hours; not more than 1 1/2 tablets in 24 hours, or as directed by a doctor
Administration:
- Dimenhydrinate comes as a tablet and chewable tablet to take by mouth with or without food.
- To prevent motion sickness, the first dose should be taken 30 minutes to 1 hour before you travel or begin motion activity.
- Adults and children older than age 12 may usually take dimenhydrinate every 4 to 6 hours as needed to prevent or treat motion sickness.
- Children under age 12 may usually be given dimenhydrinate every 6 to 8 hours as needed to prevent or treat motion sickness.
What are the dosage forms and brand names of this medicine?[edit | edit source]
This medicine is available in fallowing doasage form:
- As Dimenhydrinate 50 mg tablets
- A liquid formulation for intramuscular use is also available.
This medicine is available in fallowing brand namesː
- Dramamine; Dramamine Chewable
What side effects can this medication cause?[edit | edit source]
The most common side effects of this medicine include:
- sedation, impairment of motor function, confusion, dizziness, blurred vision, dry mouth and throat, palpitations, tachycardia, abdominal distress, constipation and headache.
- Antihistamines can worsen urinary retention and glaucoma.
Less common, but serious side effects may include:
- fast, pounding, or irregular heartbeat
What special precautions should I follow?[edit | edit source]
- Do not use for children under 2 years of age unless directed by a doctor.
Ask a doctor before use if you have:
- a breathing problem such as emphysema or chronic bronchitis
- glaucoma
- trouble urinating due to an enlarged prostate gland
- When using this product marked drowsiness may occur.
- Avoid alcoholic drinks, alcohol, sedatives, and tranquilizers may increase dizziness be careful when driving a motor vehicle or operating machinery.
- Older adults should not usually take dimenhydrinate because it is not as safe or effective as other medications that can be used to treat the same condition.
- If you have phenylketonuria, read the package label carefully before taking dimenhydrinate. Dimenhydrinate chewable tablets contain aspartame that forms phenylalanine.
- If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking dimenhydrinate.
- Talk with your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking dimenhydrinate, call your doctor.
What to do in case of emergency/overdose?[edit | edit source]
Symptoms of overdose may include:
- drowsiness or sleepiness
- difficulty speaking or swallowing
- unsteadiness
- seizures
- excitation or hyperactivity
- hallucinations
- difficulty understanding reality
- confusion
- unresponsiveness or coma
- large pupils
- flushed face
Management of overdosage:
- In case of overdose, call the poison control helpline of your country. In the United States, call 1-800-222-1222.
- Overdose related information is also available online at poisonhelp.org/help.
- In the event that the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services. In the United States, call 911.
Can this medicine be used in pregnancy?[edit | edit source]
- If you become pregnant while taking dimenhydrinate, call your doctor.
Can this medicine be used in children?[edit | edit source]
- Do not use in children under 2 years of age unless directed by a doctor.
What are the active and inactive ingredients in this medicine?[edit | edit source]
Active ingredient:
- Dimenhydrinate
Inactive ingredients:
- colloidal silicone dioxide, lactose monohydrate, magnesium stearate, microcrystalline cellulose, sodium starch glycolate, stearic acid
Who manufactures and distributes this medicine?[edit | edit source]
- Made in the for Qualitest Pharmaceuticals Huntsville, AL USA
What should I know about storage and disposal of this medication?[edit | edit source]
- store at 15° to 30°C (59° to 86°F).
First Generation Antihistamines
- Brompheniramine
- Carbinoxamine
- Chlorcyclizine
- Chlorpheniramine
- Clemastine
- Cyclizine
- Cyproheptadine
- Dexbrompheniramine
- Dexchlorpheniramine
- Dimenhydrinate
- Diphenhydramine
- Doxylamine
- Hydroxyzine
- Meclizine
- Phenyltoloxamine
- Promethazine
- Triprolidine
Second Generation Antihistamines
Dimenhydrinate Resources | ||
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