Loxapine succinate

Loxapine Succinate is an antipsychotic medication used in the treatment of schizophrenia. It belongs to the class of dibenzoxazepine derivatives and is available in oral and inhalable forms.

Pharmacology

Loxapine succinate acts by blocking the dopamine receptors in the brain, specifically D2 receptors. This action helps to normalize the chemical imbalance in the brain that leads to symptoms of schizophrenia. Loxapine also has some effect on serotonin receptors, although its exact mechanism of action is not fully understood.

Uses

Loxapine succinate is primarily used to manage the symptoms of schizophrenia. It can help to reduce hallucinations, improve concentration, and decrease feelings of agitation. It may also be used in the treatment of bipolar disorder.

Side Effects

Common side effects of loxapine succinate include drowsiness, dizziness, and dry mouth. More serious side effects can include muscle stiffness, uncontrollable movements, and rare but serious conditions such as neuroleptic malignant syndrome.

Precautions

Before starting treatment with loxapine succinate, patients should inform their healthcare provider about any existing health conditions, especially heart disease, liver disease, or a history of seizures. It is also important to discuss any other medications being taken, as loxapine can interact with many other drugs.

See Also

• Antipsychotic
• Schizophrenia
• Dopamine
• Serotonin
• Bipolar disorder
• Neuroleptic malignant syndrome