Phenergan

Phenergan is a brand name for the drug Promethazine, a first-generation antihistamine used to treat a variety of conditions, including allergies, insomnia, and nausea and vomiting related to certain conditions such as pregnancy or chemotherapy. It is also used as a sedative and for preoperative sedation.

Medical uses

Phenergan is used for a variety of medical conditions. It is primarily used to treat allergies, including hay fever, urticaria, and allergic rhinitis. It can also be used to treat insomnia, nausea and vomiting related to pregnancy or chemotherapy, and as a sedative or for preoperative sedation.

Side effects

Common side effects of Phenergan include drowsiness, dizziness, dry mouth, and blurred vision. More serious side effects can include respiratory depression, hallucinations, and severe allergic reactions.

Contraindications

Phenergan should not be used in patients with a known hypersensitivity to promethazine or to other phenothiazines. It is also contraindicated in comatose states, and in individuals known to be hypersensitive or to have had an idiosyncratic reaction to promethazine or to other phenothiazines.

Interactions

Phenergan can interact with a number of other medications, including monoamine oxidase inhibitors, anticholinergic drugs, and certain antidepressants.

Pharmacology

Phenergan works by blocking the effects of histamine, a substance produced by the body that causes many of the symptoms of an allergic reaction. It also has sedative properties, and can affect the central nervous system.

History

Phenergan was first approved for use in the United States in 1951. It is available as a generic medication.

See also

• Promethazine
• Antihistamine
• Sedative

Phenergan Resources
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